By combining genetically targeted voltage imaging with optogenetic modulation of neuronal activity in awake mice, Fan et al. dissect the circuit mechanisms by which cortical Layer 1 transforms its inputs to its outputs.
Check out the paper at: http://www.cell.com/cell/fulltext/S0092-8674(20)30047-7.
Linlin Z. Fan, Simon Kheifets, Urs L. Böhm, Hao Wu, Kiryl D. Piatkevich, Michael E. Xie, Vicente Parot, Yooree Ha, Kathryn E. Evans, Edward S. Boyden, Anne E. Takesian, and Adam E. Cohen (2019). All-Optical Electrophysiology Reveals the Role of Lateral Inhibition in Sensory Processing in Cortical Layer 1. Cell 180.
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